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Perimenopause supplements and vitamins for energy, mood and hormone balance

emily_coates

Written byEmily Coates

Dr Shazia Malik

Reviewed byDr Shazia Malik

The ultimate perimenopause stacks, 2 hands holding supplements on green background
Stack your supplements to suit your day and support every stage of perimenopause, with expert advice on choosing the right vitamins for you

Our top picks

Vegan

Holland & Barrett High Strength Complete Vit B Complex 240 Tablets
4.59

Holland & Barrett

Holland & Barrett High Strength Complete Vit B Complex 240 Tablets

3 for 2 Mix & Match

19.49

Support wellbeing during perimenopause

Starpowa Perimenopause Support 60 Gummies
4.28

Starpowa

Starpowa Perimenopause Support 60 Gummies

Buy 1 Get 1 Free

46.99

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Perimenopause can really shake things up – but it doesn’t have to throw you off balance. Stacks are a personalised bundle of vitamins and supplements taken together for a specific purpose. So, think of this as your time to stack your supplements, build a routine that works for you and truly own your perimenopause journey.

Our in-house science expert Heeral Tomlinson explains that "oestrogen levels fluctuate and gradually decline during perimenopause – a hormonal shift that can trigger changes in your cycle." So, to help you find the right perimenopause products for your needs, we also checked in with Dr Shazia Malik, obstetrician and gynaecologist. She explains that certain vitamins and minerals play key roles in supporting your body through this transition. "While many women get enough through diet, some may need a little extra support – especially when it comes to vit D and calcium," she says.

How to choose the right perimenopause product for you

As your oestrogen levels shift, nourishing your body with the right nutrients can help you feel more like yourself and support your everyday health.1 Alongside a balanced diet and lifestyle, vitamins and minerals can do more than fill nutritional gaps. They can help you build a daily ritual that supports your overall wellbeing through perimenopause, from gut health and sleep to mood and mind.

Think of this as the perfect time to stack up the essentials that work for you. Dr Malik explains: “B vitamins, like B6, can help reduce tiredness and fatigue, while vitamin C supports energy levels. Vitamin D steps in to help look after your bones and supports calcium absorption – something that becomes even more important during and after menopause, when declining oestrogen can reduce bone density and cause calcium loss from bones, even if blood calcium levels remain normal.”1,2

If you’re unsure about your levels, a home vitamin blood test can give you a clearer picture to discuss with your doctor.

Our favourite perimenopause product

Ready to start stacking up your perimenopause support? Mix and match supps to suit your routine – or your favourite flavours and formats. Let’s get stuck in with some of our top picks to support your overall wellness (and why our experts approve).

Support for your hormones

“Perimenopause is the transition phase leading up to menopause, when your hormones start to shift and your body goes through a range of changes,” explains Dr Malik. Find your flow with key nutrients involved in hormonal regulation, such as vitamin B6. This essential B vitamin helps regulate hormone activity and supports the nervous system, supporting your overall wellness during perimenopause. You can find vitamin B6 on its own or as part of a B-complex supplement, where B vitamins work together to support overall wellbeing.3-5
Holland & Barrett Vitamin B6 + Pyrixodine 12mg 60 Tablets

Supports energy levels

Holland & Barrett

4.54

€0.08/1 Tablet
Holland & Barrett High Strength Complete Vit B Complex 240 Tablets

Helps reduce tiredness

Holland & Barrett

19.49

€0.08/1 Tablet
Together Health WholeVits B Complex 30 Capsules

Contains all 8 essential B vitamins

Together Health

14.29

€0.48/1 Capsule

Supplements for skin support

Collagen levels can drop by up to 30% within the first five years of menopause,” says Heeral. “As the most abundant protein in the body, collagen naturally declines with age and one study found it continues to decrease by around 2.1% each postmenopausal year.”

Support your skin from within with key nutrients like vitamin C and zinc. Vitamin C supports normal collagen formation to help maintain skin structure, while zinc helps keep skin strong and supports healthy hair and nails. You’ll find them on their own or teamed up in targeted blends – an easy way to give your skin some love through this stage of life.
Starpowa Perimenopause Support 60 Gummies

Biotin and zinc for hair health

Starpowa

46.99

€0.21/1 Chewable
Revive Collagen Peri Menopause Hydrolysed Marine Collagen 5,000mgs 14 days Supply

With retinol and B6

Revive Collagen

47.99

€3.43/1 Sachet
Holland & Barrett Zinc 25mg 240 Tablets

High-strength zinc

Holland & Barrett

15.99

€0.07/1 Capsule

Joints, bones and muscles supplements

During menopause, your bones can lose strength fast – around 2% of bone density each year, and the drop in oestrogen can lead to an overall loss of about 10% of bone mineral density around and after menopause.6

“Calcium and vitamin D help reduce bone mineral loss in postmenopausal women and this support is achieved with a daily intake of at least 1,200mg of calcium and 20μg of vitamin D from all sources,” explains Heeral. “Both nutrients also support normal muscle function, which is particularly important as we age. Including these nutrients, alongside magnesium and protein, can help support healthy bones, joints and muscles.”6,7
Holland and Barrett Menopause Bone Nutrition Support 60 Capsules

With added Bonolive®

Holland & Barrett

32.99

€0.55/1 Capsule
Holland & Barrett Vitamin D3 4000 I.U. 100ug 120 Tablets

For bones and muscles

Holland & Barrett

20.49

€0.17/1 Tablet

Supplements to support your mind

Support your focus during perimenopause with B vitamins, make these nutrients part of your routine to help keep your mind healthy. “B vitamins play a vital role in the body, each with its own standout benefit,” says Heeral “B6 helps regulate hormonal activity, while B12 supports normal psychological function.8 It’s best to get them through your diet – but if that’s not always easy, supplements can offer support once you’ve checked with your GP.”
Holland & Barrett Vitamin B12 100ug 120 Tablets

Helps reduce tiredness

Holland & Barrett

13.64

€0.11/1 Tablet

Support with unwinding

“Around 69% of women9 experience sleep disturbances during menopause,” says Heeral. As hormone levels gradually change, this can affect the body in different ways – and it can feel different for everyone. From good sleep hygiene, such as avoiding electronic devices at least an hour before bed, to creating a peaceful sleep environment, there are a few things you can try to support your bedtime routine. That’s why gentle evening support can also be a helpful part of a calming wind-down routine.

Try starting your evening with soothing sleep gummies and valerian – a traditional herbal medicinal product used for the temporary relief of sleep disturbances and mild anxiety, based on traditional use only.9-12

Supplements to support your gut

“Emerging research suggests that gut microbiome diversity may change during menopause,” shares Heeral. Show your microbiome some love by including friendly bacteria and fibre in your routine during perimenopause and beyond.13-15
Pro-Ven For Peri/Menopause 60 Capsules

Vegetarian

PRO-VEN BIOTICS

39.99

€0.67/1 Capsule
Garden of Life Microbiome Once Daily Prenatal 30 Capsules

10 billion live bacteria strains

Garden Of Life

43.99

€1.47/1 Capsule
Holland & Barrett Live Friendly Bacteria Strawberry Flavour 60 Chewable Tablets

Extra source of L. acidophilus & BB-12

Holland & Barrett

10.39

€0.17/1 Chewable

Supplements for helping you stay calm

“During menopause, hormonal changes can influence stress levels and emotional balance, making supportive daily habits especially important,” explains Heeral. “Nutrients and traditional botanicals that help the body deal with stress. Try adding ashwagandha to your routine – a traditional herb used for centuries to help the body manage stress, support relaxation and emotional wellbeing."16-18

The final say

Building a supplement stack that works for you can make a real difference through perimenopause – whether that’s supporting hormone balance, having mindful moments, supporting your energy or giving love to your gut microbiome. Everyone’s journey is different, so it’s about finding what helps you feel more like yourself again. If perimenopause symptoms are influencing your daily routine, it’s important to check in with a healthcare professional before diving in.11,19

Your doctor can also talk you through other support options, including hormone replacement therapy (HRT) if that feels right for you. Want to learn more about the perimenopause? Get the answers to your most Googled questions.
Disclaimer – This article provides informational advice and is not a substitute for medical care. Working with experts for accuracy, we take great care to ensure the information is up-to-date and relevant. However, you should always consult your GP or healthcare professional before using supplements or alternative products, particularly if you have medical conditions or are under supervision.

Sources

1. Erdélyi A, et al. The importance of nutrition in menopause and perimenopause: a review. Nutrients. 2024;16(1):27. doi:10.3390/nu16010027
2. StatPearls Publishing. Menopause. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 [cited 2025 Jan 5]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK441912/
3. Shaver JL, Zenk SN. Sleep disturbance in menopause. In: Principles and Practice of Sleep Medicine [Internet]. Elsevier; 2008 [cited 2025 Jan 5]. Available from: https://www.sciencedirect.com/science/chapter/bookseries/abs/pii/S008367290860240X
4. StatPearls Publishing. Perimenopause. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 [cited 2025 Jan 5]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557436/
5. Patient.info. Perimenopause [Internet]. London: Patient Platform Ltd; 2024 [cited 2025 Jan 5]. Available from: https://patient.info/womens-health/perimenopause
6. Study of Women’s Health Across the Nation (SWAN). Menopause fact sheets [Internet]. 2023 [cited 2025 Jan 5]. Available from: https://www.swanstudy.org/wps/wp-content/uploads/2023/12/SWANFactSheets2023.pdf
7. Baker FC, et al. Sleep problems during the menopausal transition: prevalence, impact, and management challenges. Nat Sci Sleep. 2021;13:73–95. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC8313472/
8. StatPearls Publishing. Sleep disorders in women. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 [cited 2025 Jan 5]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK559132/
9. Khan A. The hidden link between menopause and sleep problems [Internet]. Sleep Psychiatrist; 2023 [cited 2025 Jan 5]. Available from: https://sleeppsychiatrist.com/blog/the-hidden-link-between-menopause-and-sleep-problems/
10. NHS. How to fall asleep faster and sleep better [Internet]. London: NHS; 2024 [cited 2025 Jan 5]. Available from: https://www.nhs.uk/every-mind-matters/mental-wellbeing-tips/how-to-fall-asleep-faster-and-sleep-better/
11. NHS. Menopause: symptoms [Internet]. London: NHS; 2024 [cited 2025 Jan 5]. Available from: https://www.nhs.uk/conditions/menopause/symptoms/
12. Worsley R, et al. Global cross-sectional survey of women with menopausal symptoms: prevalence, severity and treatment patterns. Menopause. 2021;28(8):875–84. Available from: https://journals.lww.com/menopausejournal/fulltext/2021/08000/global_cross_sectional_survey_of_women_with.7.aspx
13. Avis NE, et al. Sleep disturbance symptoms among midlife women. J Womens Health. 2022;31(9):1235–45. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC9379122/
14. Li S, et al. The association between menopause and sleep quality: a cross-sectional study. BMC Womens Health. 2022;22:356. doi:10.1186/s12905-022-02029-w
15. Santoro N, et al. Spotlight on the gut microbiome in menopause: current insights. Int J Womens Health. 2022;14:1087–1102. Available from: https://www.dovepress.com/spotlight-on-the-gut-microbiome-in-menopause-current-insights-peer-reviewed-fulltext-article-IJWH16. Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012;34(3):255–62.
17. KSM-66 Ashwagandha. What is KSM-66? [Internet]. 2024 [cited 2025 Jan 5]. Available from: https://ksm66ashwagandhaa.com/what-is-ksm66.php
18. National Institutes of Health, Office of Dietary Supplements. Ashwagandha: health professional fact sheet [Internet]. Bethesda (MD): NIH; 2024 [cited 2025 Jan 5]. Available from: https://ods.od.nih.gov/factsheets/Ashwagandha-HealthProfessional/19. NHS. Herbal remedies and complementary medicines for menopause symptoms [Internet]. London: NHS; 2024 [cited 2025 Jan 5]. Available from: https://www.nhs.uk/medicines/hormone-replacement-therapy-hrt/alternatives-to-hormone-replacement-therapy-hrt/herbal-remedies-and-complementary-medicines-for-menopause-symptoms/
 
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